Febuxostat prevented early gout flares YOUR DOSE OF MEDICINE - Charles C. Chante MD (The Philippine Star) - August 19, 2018 - 12:00am The urate-lowering therapy febuxostat reduced the number of disease flares that the people with early gout experienced, relative to placebo, in a double-blind study. Febuxostat (Uloric) produced a 12.1 percent reduction in the overall percentage of patients who experienced at least one gout flare, in comparison with placebo (29.3 percent vs. 41.4 percent; P<.05). Treatment with febuxostat also significantly improved control of serum uric acid, compared with the placebo-treated patients (64.3 percent vs. 5.7 percent;P<.001), as well as synovitis as measured via the rheumatoid arthritis magnetic resonance imaging score (RAMRIS) (-0.43 vs. -0.07; P<.001). Current clinical practice guidelines do not recommend routine use of urate-lowering therapy for people after their first gout … [Read more...] about Febuxostat prevented early gout flares
Double blind study
(THE STAR/ASIA NEWS NETWORK) - A curious aspect of non-coeliac gluten sensitivity (NCGS) is that this syndrome is usually acquired after childhood. It is odd because statistically, adults have a smaller percentage of allergy sufferers than children – one presumes childhood allergens are better tolerated as one grows older and develops a more rounded (or stronger) immune system. It might be suggested that NCGS is akin to lactose intolerance, which develops after the body stops producing the enzyme lactase. The difference is the human body is innately unable to produce the enzymes to digest many complex carbohydrates at any age – it needs bacteria in the human gastrointestinal microbiota (HGM) to do this, and one supposes adults have a larger range of bacterial fauna than children. To be clear, humans do produce enzymes to digest some common carbohydrates, especially starches (made up of amylose and amylopectin) and sugars – but most other carbohydrates need digestive … [Read more...] about Could there be a link between new wheat and gluten sensitivity?
By Jayme Poisson Investigative Reporter David Bruser Investigative Reporter Thu., May 24, 2018 More than four decades after mercury was dumped upstream from Grassy Narrows First Nation, the physical and mental health of the people there is by many key measures “considerably worse” than that of other First Nations in Canada, according to a landmark new government-funded survey. The survey found there are fewer elders in Grassy Narrows, suggesting people there are dying prematurely. The residents are also reporting higher rates of suicidal thoughts and suicide attempts compared to other First Nations. And adult residents who reported eating more fish as children had experienced lower levels of success in school and have higher rates of nervous system symptoms and disorders. “The results of the (survey) provide clear evidence that the physical and mental health of (Grassy Narrows community) members is poorer than that of other … [Read more...] about Landmark study reveals ‘clear evidence’ of mercury’s toll on health in Grassy Narrows
By Megan Ogilvie Health Reporter Mon., April 23, 2018 Dr. Brian Goldman wanted to rediscover how to be kind. The emergency room physician at Toronto’s Mount Sinai Hospital knew he was a thoughtful doctor and a caring husband and father. But he wondered whether his 30 years of treating patients in a busy downtown hospital had worn away his empathy. Those brooding thoughts turned into a two-year search for kindness that took him across Canada and around the world. On his travels, Goldman, who is also the host of CBC Radio’s White Coat, Black Art, interviewed top neuroscientists, hung out in laboratories and underwent psychological testing to determine his own capacity for kindness. Read more: Dr. Brian Goldman shares physician slang in new book Article Continued Below Why this MD and broadcaster lives beneath his means Doctor heeds siren call of emergency room But even more important to his pursuit, he says, were the extraordinarily kind … [Read more...] about Doctor chronicles journey back to kindness in new book
caption Jordan Michelle vapes a CBD oil made from hemp at the Cannabis World Congress Conference. source Spencer Platt/Getty States around the country – 29 of them, plus Washington DC – have legalized medical marijuana. The American public largely supports the legalization of medical marijuana. At least 84% of the public believes the drug should be legal for medical uses, and recreational pot usage is less controversial than ever, with at least 61% of Americans in support. Even though some medical benefits of smoking pot may be overstated by advocates of marijuana legalization, recent research has demonstrated that there are legitimate medical uses for marijuana and strong reasons to continue studying the drug’s medicinal uses. Even the NIH’s National Institute on Drug Abuse lists medical uses for cannabis. There are at least two active chemicals in marijuana that researchers think have medicinal applications. Those are cannabidiol … [Read more...] about 23 health benefits of marijuana