What is different about Phase-3 part of the trial?Each of these stages can take several months and that includes the time taken to recruit patients as well as the time involved in observing the effects of drugs and vaccines at various intervals of time. Such data is again sent to regulators, who, if satisfied, give the green signal for Phase-3. In this stage, the drug or vaccine is tested at multiple locations in thousands of volunteers or patients. In the case of a drug, this is the stage when a new drug is compared to the existing standard of care and when it must prove that it is either more efficacious, or is of similar potency but is safer, better tolerable or delivers any of the goods that the drugmakers had claimed when making the drug. In the case of a vaccine for a new disease, there is usually nothing to compare it to, so Phase-3 becomes a larger version of the Phase-2 trial. A Phase-3 trial is held at multiple locations to capture the demographic variability in the … [Read more...] about The Hindu Explains | Why is Phase-3 of COVID-19 vaccine trial complicated?
When will adnan syed get a new trial
New Delhi: The Transport Department of the Delhi government has started second phase trial of contactless e-ticketing app in its cluster buses. Delhi Transport Minister Kailash Gahlot said on Monday a total of 2,000 tickets including 1,500 pink ones were transacted through the app on the first day of the second phase trial. Transport Department officials said the scope of the trial has been widened by covering more buses. "The second phase trial will go on for a week and 300 cluster buses will be covered in it. In the first phase trial in August, buses of only one route were covered," they said. The first phase trial of the contactless e-ticketing app was carried out amid the COVID-19 pandemic to prevent the spread of the infection among the commuters. The officials said the second phase trial of the app will cover 14 routes, and the shortcomings noticed during the first phase will be rectified in it. Majority of app users in the first phase trial had found the app easy to download … [Read more...] about Delhi Transport Dept begins Ph-2 trial of contactless e-ticketing app in cluster buses
With 167 of the 2,000 sevayats or priests of the 12th century Jagannath temple in Puri infected by Covid-19, the opening of the temple to public now seems to be shrouded in uncertainty. On August 31, the state government had decided that none of the religious places in the state will be opened till September 30. Read more … [Read more...] about News updates from Hindustan Times: Fugitive Nirav Modi will not get fair trial in India, says former SC judge and all the latest news
Investigating whether an adverse effect is or is not be related to the vaccine must be done to establish its safety. “The trials can be resumed only if the cause of the adverse event is unrelated to the vaccine. You can compromise on efficacy and produce a vaccine that has 70% efficacy, but you can’t take a chance with 100% safety,” said Dr Randeep Guleria, director, All India Institute of Medial Sciences, New Delhi, which is one of the dozen sites for the Indian Council of Medical Research-Bharat Biotech Covaxin, which began Phase 2 trials this week. … [Read more...] about AstraZeneca pauses trials after ‘unexplained illness’
Covid-19: the current count in IndiaThe novel coronavirus (Covid-19) in India has infected 4,277,584 people. Of this 3,321,420 people have recovered whereas 72,816 persons have been killed as per the latest update from the Health Ministry. Around the world, the virus has infected 27,485,894 and killed 896,844 people.Covid trials & tribulationsExperimenting with immunity boosting drugs, Health and wellness firm Hamdard Laboratories has received regulatory approvals from the Ministry of AYUSH and Institutional Ethics Committee of HAH Centenary Hospital, New Delhi to begin trials for its Infuza and Kulzam drugs. A research team from Hamdard Institute of Medical Sciences and Research (HIMSR) is going to start the clinical trials. The trials are aimed at testing the efficacy of these drugs for the prevention of Covid-19 infection in high risk subjects. "A research group of HIMSR, that comprises an allopathic doctor, unani hakim, microbiologist and biochemist is working on a randomised, … [Read more...] about Covid Speed Read: Oxford vaccine trials in India delayed over safety approvals; China to show-off domestic vaccines at Beijing trade fair